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The focus of Article 5 in the Constitution is indeed on the amendment process. This article outlines the procedures by which the Constitution can be amended, highlighting the balance between the need for a stable governance framework and the flexibility to adapt to changing circumstances or societal needs.

Article 5 specifies two methods for proposing amendments: either by a two-thirds vote in both houses of Congress or by a convention called for by two-thirds of state legislatures. It also outlines the ratification process, which can be achieved through the approval of three-fourths of state legislatures or conventions. This careful structuring allows for both ease of change when necessary and a high standard for making significant changes to the nation's foundational legal document, ensuring that amendments reflect a broad consensus.

The other topics mentioned, such as national supremacy, judicial review, and state relations, are addressed in different parts of the Constitution. National supremacy is primarily covered in Article 6, judicial review, while not explicitly stated in the Constitution, has been established through case law, particularly in Marbury v. Madison, and state relations are primarily addressed in Article 4. Each of these articles serves different fundamental aspects of the Constitution, but Article 5's distinct focus on amending the Constitution sets it apart in